FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170

FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

EXTRACTION, ISOLATION AND CHARACTERIZATION OF SOME ALKALOIDS FROM THE BARK OF Pericopsis laxiflora (FAMILY: FABACEAE)
Pages: 146-150
A. L. Fadipe, A. Mann, F. Isah and A. O. Akande


keywords: Alkaloids, bark, ethanol extract, isolation, Pericopsislaxiflora, spectral analysis

Abstract

Extraction and purification of some of the nitrogenous bases present in the bark of Pericopsislaxifloraled to the isolation and characterization of three alkaloids. The structures of the isolated compounds on the basis of physical, chemical and spectral techniques, such as IR, UV, 1H-NMR, 13C-NMR, Dept-135 and GC-MS were elucidated as 5,8-Dimethyl-1,2,3,4-tetrahydro-9-acridinamine (1), 4,6-Diaminopyrazolo[3,4-d] pyrimidine (2) and 1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a]diazocin-8-one (3).The presence of these nitrogenous bases, with many more yet to be isolated and characterized, is an indication that the plant may provide drugs that will help increase the therapeutic arsenal.

References

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